TY - JOUR
T1 - Plasma pseudo cholinesterase deficiency leading to seven hour apnoea in a child undergoing adeno-tonsillectomy
AU - Bhargava, Deepa
AU - Sharma, Jasvinder
AU - Al-Abri, Rashid
PY - 2012/1
Y1 - 2012/1
N2 - Objective: We report a rare, silent, potentially fatal operative complication of seven hour apnoea in a patient undergoing adenotonsillectomy secondary to deficiency of plasma cholinesterase. Awareness of this hereditary disorder is important to otolaryngologist as; it is difficult to diagnose, can be unexpectedly alarming for parents and the surgeon. Methods: Case report and review of world literature. Results: A four-year male with obstructive sleep apnoea underwent a routine elective adenotonsillectomy; there was no spontaneous recovery of respiration following surgery. He was transferred to the intensive care unit and 7. h later was successfully weaned from the ventilator and extubated. A plasma cholinesterase level of 4561. U/L was discovered much later. Conclusion: To our knowledge this is the first case report of pseudo cholinesterase deficiency reported in otolaryngology literature and first in Oman. The patient should receive information about the condition, the associated risks, inheritance and need for testing other family members.
AB - Objective: We report a rare, silent, potentially fatal operative complication of seven hour apnoea in a patient undergoing adenotonsillectomy secondary to deficiency of plasma cholinesterase. Awareness of this hereditary disorder is important to otolaryngologist as; it is difficult to diagnose, can be unexpectedly alarming for parents and the surgeon. Methods: Case report and review of world literature. Results: A four-year male with obstructive sleep apnoea underwent a routine elective adenotonsillectomy; there was no spontaneous recovery of respiration following surgery. He was transferred to the intensive care unit and 7. h later was successfully weaned from the ventilator and extubated. A plasma cholinesterase level of 4561. U/L was discovered much later. Conclusion: To our knowledge this is the first case report of pseudo cholinesterase deficiency reported in otolaryngology literature and first in Oman. The patient should receive information about the condition, the associated risks, inheritance and need for testing other family members.
KW - Adenotonsillectomy
KW - Prolonged apnoea
KW - Pseudo cholinesterase
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U2 - 10.1016/j.ijporl.2011.10.010
DO - 10.1016/j.ijporl.2011.10.010
M3 - Article
C2 - 22051140
AN - SCOPUS:84855562104
SN - 0165-5876
VL - 76
SP - 149
EP - 151
JO - International Journal of Pediatric Otorhinolaryngology
JF - International Journal of Pediatric Otorhinolaryngology
IS - 1
ER -