Insights into organoid-based modeling of COVID-19 pathology

Mohadese Hashem Boroojerdi, Tariq Al Jabry, Seyed Mohamad Javad Mirarefin, Halima Albalushi*

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةReview articleمراجعة النظراء


Since December 2019, various types of strategies have been applied due to the emergent need to investigate the biology and pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to discover a functional treatment. Different disease modeling systems, such as mini-organ technology, have been used to improve our understanding of SARS-CoV-2 physiology and pathology. During the past 2 years, regenerative medicine research has shown the supportive role of organoid modeling in controlling coronavirus disease 2019 (COVID-19) through optimal drug and therapeutic approach improvement. Here, we overview some efforts that have been made to study SARS-CoV-2 by mimicking COVID-19 using stem cells. In addition, we summarize a perspective of drug development in COVID-19 treatment via organoid-based studies.

اللغة الأصليةEnglish
رقم المقال37
دوريةVirology Journal
مستوى الصوت20
رقم الإصدار1
المعرِّفات الرقمية للأشياء
حالة النشرPublished - ديسمبر 2023
منشور خارجيًانعم

ASJC Scopus subject areas

  • ???subjectarea.asjc.2400.2406???
  • ???subjectarea.asjc.2700.2725???

قم بذكر هذا