Influence of auto-antibody specificities on the clinical course in patients with chronic and acute ITP

Y. S. Mehta*, A. V. Pathare, S. S. Badakere, K. Ghosh, Dipika Mohanty

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

19 اقتباسات (Scopus)

ملخص

It is now well established that the target antigens of platelet auto-antibodies are the GP IIb/IIIa and GP Ib/IX receptors. In our study, it was observed that the majority of patients had antibodies directed towards the GP IIb/IIIa receptor, whereas the number of patients having antibodies directed towards the GP Ib/IX receptor was much less. Also, we found that the patients in whom the auto-antibodies are directed towards the GP IIb/IIIa receptors usually have mild bleeding. On the other hand, the patients having auto-antibodies directed towards both GP IIb/IIIa and GP Ib/IX receptors have a severe bleeding diathesis, and usually show poor prognosis to treatment with corticosteroids.

اللغة الأصليةEnglish
الصفحات (من إلى)94-98
عدد الصفحات5
دوريةPlatelets
مستوى الصوت11
رقم الإصدار2
المعرِّفات الرقمية للأشياء
حالة النشرPublished - 2000
منشور خارجيًانعم

ASJC Scopus subject areas

  • ???subjectarea.asjc.2700.2720???

بصمة

أدرس بدقة موضوعات البحث “Influence of auto-antibody specificities on the clinical course in patients with chronic and acute ITP'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا