Emergence of West Nile virus lineage 2 in Europe: Characteristics of the first seven cases of West Nile neuroinvasive disease in horses in Austria

Phebe de Heus, Jolanta Kolodziejek, Jeremy V. Camp, Katharina Dimmel, Zoltán Bagó, Zdenek Hubálek, René van den Hoven, Jessika M.V. Cavalleri, Norbert Nowotny*

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

16 اقتباسات (Scopus)

ملخص

We report details of the first seven equine cases of confirmed West Nile neuroinvasive disease in Austria. The cases presented during summer and autumn of 2016 (n = 2), 2017 (n = 3) and 2018 (n = 2). All horses showed gait abnormalities and 6 of 7 horses exhibited fasciculations and/or tremors, and we provide video recordings of these. Three horses also showed cranial nerve involvement. Following rapid improvement, three horses were discharged. Four horses were euthanized due to the severity of clinical signs and subjected to neuropathological examination. West Nile virus (WNV) lineage 2 nucleic acid was detected in 5 of 7 horses, and WNV-specific neutralizing antibodies in all 7 horses. In addition, serologic evidence of WNV infection was found in two out of fourteen in-contact horses. Horses may be considered a sentinel species for human WNV infections, integrating human and veterinary medicine and thus contributing to the one health concept.

اللغة الأصليةEnglish
الصفحات (من إلى)1189-1197
عدد الصفحات9
دوريةTransboundary and Emerging Diseases
مستوى الصوت67
رقم الإصدار3
المعرِّفات الرقمية للأشياء
حالة النشرPublished - مايو 1 2020
منشور خارجيًانعم

ASJC Scopus subject areas

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بصمة

أدرس بدقة موضوعات البحث “Emergence of West Nile virus lineage 2 in Europe: Characteristics of the first seven cases of West Nile neuroinvasive disease in horses in Austria'. فهما يشكلان معًا بصمة فريدة.

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