Effect of deltamethrin on the liver and ovary of Aphanius dispar: A microscopic study

Ultrastructural alterations were observed in the liver and the ovary of Aphanius dispar exposed to different concentrations of deltamethrin (2.25, 2.50 and 3.00 μg/L) The hepatocytes of the liver showed an increase in cytoplasmic lipid droplets, mitochondria, reduction in the amount of rough endoplasmic reticulum (RER), and ar increase in the numbers of secondary lysosomes with degraded cell organelles. Chromatin condensation of the nuclei was also seen. A marked increase of the interhepatocyte space was observed. The common changes observed in the ovary were the increase in the number of secondary growth oocytes, the number of atresian follioles, and the decrease in the number of primary growth oocytes. The highest secondary to primary growth oocytes ratio was found in fish exposed to 3.00 μg/L deltamethrin. There was no development beyond the secondary growth oocytes stage in fish exposed to all concentrations of deltamethrin.