Ecthyma contagiosum (orf) - Report of a human case from the United Arab Emirates and review of the literature

Suhail Al-Salam, Norbert Nowotny, Mohammed Rizwan Sohail, Jolanta Kolodziejek, Thomas G. Berger

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

39 اقتباسات (Scopus)


Background: Ecthyma contagiosum (orf) is caused by an epitheliotropic parapox virus. It is a zoonosis usually transmitted to humans from affected sheep or goat through direct contact or contaminated fomites. Methods: We report a 36-year-old patient with multiple skin lesions on his left hand, first observed 5 days before admission followed by red streaks on the forearm and an erythema on the upper arm 1 day prior to admission. The patient reported that he was working on a sheep farm. Results: Histopathologic examination showed evidence of a viral infection. Subsequent transmission electron microscopy showed typical parapox virus particles, predominantly in the scaled-off layers of degenerated keratinocytes and monocytes. The results were verified and specified by two newly established polymerase chain reaction (PCR) assays and subsequent sequencing of the amplicons: one broadly reacting 'general parapox virus PCR', and one assay which allows - following sequencing - discrimination between individual orf virus strains. Conclusion: Despite the multiplicity of the lesions, there was a significant improvement after 2 weeks of treatment. Sequencing showed the uniqueness of this virus compared with previously published strains from other countries.

اللغة الأصليةEnglish
الصفحات (من إلى)603-607
عدد الصفحات5
دوريةJournal of Cutaneous Pathology
مستوى الصوت35
رقم الإصدار6
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يونيو 2008
منشور خارجيًانعم

ASJC Scopus subject areas

  • ???subjectarea.asjc.2700.2734???
  • ???subjectarea.asjc.2700.2722???
  • ???subjectarea.asjc.2700.2708???


أدرس بدقة موضوعات البحث “Ecthyma contagiosum (orf) - Report of a human case from the United Arab Emirates and review of the literature'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا