Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

Abdul Hakeem Al Hashim; Ibrahim Al-Zakwani; Abdullah Al Jadidi; Ruqaiya Al Harthi; Maadh Al Naabi; Ramakrishna Biyappu; Sonali Kodange; Naveen Kumar Asati; Tamadher Al Barhi; Mudhun Mohan; Jayachandiran Jagadeesan; Micheline Sachez; Praisemabel S. Sycaayao; Khalfan Al Amrani; Huda Al Khalili; Rashid Al Mamari; Mujahid Al-Busaidi

doi:10.5001/omj.2023.52

Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

Abdul Hakeem Al Hashim^*, Ibrahim Al-Zakwani, Abdullah Al Jadidi, Ruqaiya Al Harthi, Maadh Al Naabi, Ramakrishna Biyappu, Sonali Kodange, Naveen Kumar Asati, Tamadher Al Barhi, Mudhun Mohan, Jayachandiran Jagadeesan, Micheline Sachez, Praisemabel S. Sycaayao, Khalfan Al Amrani, Huda Al Khalili, Rashid Al Mamari, Mujahid Al-Busaidi^*

^*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلة › Article › مراجعة النظراء

1 اقتباس (Scopus)

ملخص

OBJECTIVES: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.

METHODS: We conducted a retrospective study using data from intensive care units of two tertiary centers in Oman. Adult patients with moderate to severe COVID-19-related ARDS with a PaO2/FiO2 ratio < 150 on FiO2 of 60% or more and a positive end-expiratory pressure of at least 8 cm H2O who were admitted between 1 May 2020 and 31 October 2020 were selected as participants. All patients were intubated and subjected to mechanical ventilation within 48 hours of admission and placed in either prone or supine position. Mortality was measured and compared between the patients from the two groups.

RESULTS: A total of 235 patients were included (120 in the prone group and 115 in the supine group). There were no significant differences in mortality (48.3% vs. 47.8%; p =0.938) and discharge rates (50.8% vs. 51.3%; p =0.942) between the prone and supine groups, respectively.

CONCLUSIONS: Early prone positioning of patients with COVID-19-related ARDS does not result in a significant reduction in mortality.

اللغة الأصلية	English
رقم المقال	e465
الصفحات (من إلى)	e465
دورية	Oman Medical Journal
مستوى الصوت	38
رقم الإصدار	1
المعرِّفات الرقمية للأشياء	https://doi.org/10.5001/omj.2023.52
حالة النشر	Published - يناير 31 2023

ASJC Scopus subject areas

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الوصول إلى المستند

10.5001/omj.2023.52

الملفات والروابط الأخرى

قم بذكر هذا

Al Hashim, A. H., Al-Zakwani, I., Al Jadidi, A., Al Harthi, R., Al Naabi, M., Biyappu, R., Kodange, S., Asati, N. K., Al Barhi, T., Mohan, M., Jagadeesan, J., Sachez, M., Sycaayao, P. S., Al Amrani, K., Al Khalili, H., Al Mamari, R., & Al-Busaidi, M. (2023). Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome. Oman Medical Journal, 38(1), e465. المقال e465. https://doi.org/10.5001/omj.2023.52

Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome. / Al Hashim, Abdul Hakeem ; Al-Zakwani, Ibrahim; Al Jadidi, Abdullah وآخرون.
في: Oman Medical Journal, المجلد 38, رقم 1, e465, ٣١.٠١.٢٠٢٣, صفحة e465.

نتاج البحث: المساهمة في مجلة › Article › مراجعة النظراء

Al Hashim, AH , Al-Zakwani, I, Al Jadidi, A, Al Harthi, R, Al Naabi, M, Biyappu, R, Kodange, S, Asati, NK, Al Barhi, T, Mohan, M, Jagadeesan, J, Sachez, M, Sycaayao, PS, Al Amrani, K, Al Khalili, H, Al Mamari, R & Al-Busaidi, M 2023, 'Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome', Oman Medical Journal, المجلد 38, رقم 1, e465, الصفحات e465. https://doi.org/10.5001/omj.2023.52

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title = "Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome",

abstract = "OBJECTIVES: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.METHODS: We conducted a retrospective study using data from intensive care units of two tertiary centers in Oman. Adult patients with moderate to severe COVID-19-related ARDS with a PaO2/FiO2 ratio < 150 on FiO2 of 60% or more and a positive end-expiratory pressure of at least 8 cm H2O who were admitted between 1 May 2020 and 31 October 2020 were selected as participants. All patients were intubated and subjected to mechanical ventilation within 48 hours of admission and placed in either prone or supine position. Mortality was measured and compared between the patients from the two groups.RESULTS: A total of 235 patients were included (120 in the prone group and 115 in the supine group). There were no significant differences in mortality (48.3% vs. 47.8%; p =0.938) and discharge rates (50.8% vs. 51.3%; p =0.942) between the prone and supine groups, respectively. CONCLUSIONS: Early prone positioning of patients with COVID-19-related ARDS does not result in a significant reduction in mortality.",

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T1 - Early Prone versus Supine Positioning in Moderate to Severe Coronavirus Disease 2019 Patients with Acute Respiratory Distress Syndrome

AU - Al Hashim, Abdul Hakeem

AU - Al-Zakwani, Ibrahim

AU - Al Jadidi, Abdullah

AU - Al Harthi, Ruqaiya

AU - Al Naabi, Maadh

AU - Biyappu, Ramakrishna

AU - Kodange, Sonali

AU - Asati, Naveen Kumar

AU - Al Barhi, Tamadher

AU - Mohan, Mudhun

AU - Jagadeesan, Jayachandiran

AU - Sachez, Micheline

AU - Sycaayao, Praisemabel S.

AU - Al Amrani, Khalfan

AU - Al Khalili, Huda

AU - Al Mamari, Rashid

AU - Al-Busaidi, Mujahid

PY - 2023/1/31

Y1 - 2023/1/31

N2 - OBJECTIVES: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.METHODS: We conducted a retrospective study using data from intensive care units of two tertiary centers in Oman. Adult patients with moderate to severe COVID-19-related ARDS with a PaO2/FiO2 ratio < 150 on FiO2 of 60% or more and a positive end-expiratory pressure of at least 8 cm H2O who were admitted between 1 May 2020 and 31 October 2020 were selected as participants. All patients were intubated and subjected to mechanical ventilation within 48 hours of admission and placed in either prone or supine position. Mortality was measured and compared between the patients from the two groups.RESULTS: A total of 235 patients were included (120 in the prone group and 115 in the supine group). There were no significant differences in mortality (48.3% vs. 47.8%; p =0.938) and discharge rates (50.8% vs. 51.3%; p =0.942) between the prone and supine groups, respectively. CONCLUSIONS: Early prone positioning of patients with COVID-19-related ARDS does not result in a significant reduction in mortality.

AB - OBJECTIVES: This study sought to determine whether early prone positioning of patients with moderate to severe COVID-19-related acute respiratory distress syndrome (ARDS) lowers the mortality rate.METHODS: We conducted a retrospective study using data from intensive care units of two tertiary centers in Oman. Adult patients with moderate to severe COVID-19-related ARDS with a PaO2/FiO2 ratio < 150 on FiO2 of 60% or more and a positive end-expiratory pressure of at least 8 cm H2O who were admitted between 1 May 2020 and 31 October 2020 were selected as participants. All patients were intubated and subjected to mechanical ventilation within 48 hours of admission and placed in either prone or supine position. Mortality was measured and compared between the patients from the two groups.RESULTS: A total of 235 patients were included (120 in the prone group and 115 in the supine group). There were no significant differences in mortality (48.3% vs. 47.8%; p =0.938) and discharge rates (50.8% vs. 51.3%; p =0.942) between the prone and supine groups, respectively. CONCLUSIONS: Early prone positioning of patients with COVID-19-related ARDS does not result in a significant reduction in mortality.

KW - COVID-19

KW - Oman

KW - Positive-Pressure Respiration

KW - Prone Position

KW - Respiratory Distress Syndrome

KW - Retrospective Studies

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