Coronary artery bypass grafting in a patient with protein S deficiency: Perioperative implications

Baskaran Balan*, Suresh Chengode, Hilal Al Sabti, Ram Narayan Rao

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

1 اقتباس (Scopus)

ملخص

Protein S (PS) along with activated protein C plays an important role in the down-regulation of in vivo thrombin generation. Its deficiency can cause abnormal and inappropriate clot formation within the circulation necessitating chronic anticoagulation therapy. The risk of developing thrombotic complications is heightened in the perioperative period in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Heparin resistance is very rare in these patients, especially when antithrombin levels are near normal. Management of CPB in this scenario is quite challenging. We report the perioperative management, particularly the CPB management, of a patient with type I PS deficiency and incidentally detected heparin resistance, who underwent coronary artery bypass grafting with CPB.

اللغة الأصليةEnglish
الصفحات (من إلى)232-236
عدد الصفحات5
دوريةAnnals of Cardiac Anaesthesia
مستوى الصوت17
رقم الإصدار3
المعرِّفات الرقمية للأشياء
حالة النشرPublished - 2014

ASJC Scopus subject areas

  • ???subjectarea.asjc.2700.2705???
  • ???subjectarea.asjc.2700.2703???

بصمة

أدرس بدقة موضوعات البحث “Coronary artery bypass grafting in a patient with protein S deficiency: Perioperative implications'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا