Complexes of cobalt(III) with phenolate-containing polydentate ligands and bovine serum apo-transferrin: Towards creating spectroscopic models for cobalt(III)-tyrosinate interactions

Musa S. Shongwe*, Said K.M. Al-Hatmi, Helder M. Marques, Rachel Smith, Ryoji Nukada, Masahiro Mikuriya

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

14 اقتباسات (Scopus)

ملخص

Reaction of each member of a series of variously substituted N-(2-hydroxybenzyl)glycinate (hbg2-) ligands [5-bromo- (5-Br-hbg2-); 5-chloro- (5-Cl-hbg2-); 3,5-dichloro- (3,5-Cl2-hbg2-); 5-chloro-3-methyl- (5,3-Cl,Me-hbg2-); and 3,5-dimethyl- (3,5-Me2-hbg2-)] with cobalt(II) in stoichiometric amounts under ambient conditions afforded the CoIII complex anions of the general formulatrans,trans,trans-[Co(hbg)2]-. Single-crystal X-ray analyses of [C5H10NH2]-trans,trans,trans-[Co(3,5-Cl 2-hbg)2]3 and [C5H10NH2]-trans,trans,trans-[Co(3,5-Me 2-hbg)2]5 {[C5H10- NH2] piperidinium counter ion} have revealed similar structural motifs of these compounds. Each of the crystal structures shows two non-equivalent complex anions in the unit cell connected through hydrogen bondingvia the piperidinium cation. The two hbg2- ligands in each complex ion are arranged facially around the cobalt(III) ion and each ligand employs a phenolate oxygen, an amine nitrogen and a carboxylate oxygen to form a distorted octahedral geometry with Ci symmetry. These compounds (1-5) serve as spectroscopic models for the interaction of cobalt(III) with tyrosinate ligands. The electronic spectrum of the compound [C5H10NH2]-trans,trans,trans-[Co(5,3-Cl, Me-hbg)2]4 bears a striking resemblance to that of the complex of cobalt(III) with bovine serum transferrin, [Co2BTf]. In contrast to previous studies on the spectroscopy of the transferrins, one of the two ligand-field transitions expected to occur in [Co2BTf] is evident in the electronic spectrum of this derivative of bovine serum transferrin in vitro. One of the fascinating characteristics of thetrans,trans,trans-[Co(hbg)2]- model system is the solvent dependence of the optical spectra.

اللغة الأصليةEnglish
الصفحات (من إلى)4064-4069
عدد الصفحات6
دوريةJournal of the Chemical Society, Dalton Transactions
رقم الإصدار21
المعرِّفات الرقمية للأشياء
حالة النشرPublished - 2002

ASJC Scopus subject areas

  • ???subjectarea.asjc.1600.1600???

بصمة

أدرس بدقة موضوعات البحث “Complexes of cobalt(III) with phenolate-containing polydentate ligands and bovine serum apo-transferrin: Towards creating spectroscopic models for cobalt(III)-tyrosinate interactions'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا