TY - JOUR
T1 - Comparison between helicobacter pylori fecal antigen detection and endoscopic gastric biopsy in diagnosis of H. pylori infection in 50 adult cases
AU - Siddiqui, Aftab Ahmed
AU - Ansari, Moin Ahmed
AU - Rahman, Raja Ur
AU - Jabeen, Rakhshinda
AU - Qureshi, Naveed Rashid
AU - Kashoob, Masoud Bakheet
PY - 2010/1
Y1 - 2010/1
N2 - OBJECTIVE: To compare the effectiveness of fecal antigen detection test with gastric biopsy via upper gi endoscopy for H pylori. DESIGN: Comparative, observational, non- randomized.&PLACE AND DURATION OF STUDYS: Sultan Qaboos University Hospital, Oman. February 2005 -February 2006. PATIENTS AND METHODS: Fifty patients with epigastric pain and heart burn were subjected to upper gi endoscopy and gastric biopsy for H. pylori and at the same time stool was sent for fecal antigen detection for H. pylori. RESULTS: Out of 30 females, 12 had biopsy proven H. pylori while 5 had positive fecal antigen test. In 20 male patients, 15 had positive biopsy while 12 had fecal antigen proven H. pylori. CONCLUSION: This study doesn't prove the effectiveness of fecal antigen detection test in comparison with upper gi endoscopy and biopsy, which is the gold standard test for H. pylori. Hence we cannot recommend the test to replace upper gi endoscopy and biopsy despite of the low cost and less trouble to the patient.
AB - OBJECTIVE: To compare the effectiveness of fecal antigen detection test with gastric biopsy via upper gi endoscopy for H pylori. DESIGN: Comparative, observational, non- randomized.&PLACE AND DURATION OF STUDYS: Sultan Qaboos University Hospital, Oman. February 2005 -February 2006. PATIENTS AND METHODS: Fifty patients with epigastric pain and heart burn were subjected to upper gi endoscopy and gastric biopsy for H. pylori and at the same time stool was sent for fecal antigen detection for H. pylori. RESULTS: Out of 30 females, 12 had biopsy proven H. pylori while 5 had positive fecal antigen test. In 20 male patients, 15 had positive biopsy while 12 had fecal antigen proven H. pylori. CONCLUSION: This study doesn't prove the effectiveness of fecal antigen detection test in comparison with upper gi endoscopy and biopsy, which is the gold standard test for H. pylori. Hence we cannot recommend the test to replace upper gi endoscopy and biopsy despite of the low cost and less trouble to the patient.
KW - Endoscopy
KW - Epigastric pain
KW - Fecal antigen detection test
KW - H. pylori
KW - Heart burn
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M3 - Article
AN - SCOPUS:77954163785
SN - 1729-0341
VL - 9
SP - 23
EP - 26
JO - Journal of the Liaquat University of Medical and Health Sciences
JF - Journal of the Liaquat University of Medical and Health Sciences
IS - 1
ER -