@article{7418059470e64143ba286460119f20d4,
title = "Clinical presentation and outcomes of peripartum cardiomyopathy in the Middle East: a cohort from seven Arab countries",
abstract = "Aims: Published data on the clinical presentation of peripartum cardiomyopathy (PPCM) are very limited particularly from the Middle East. The aim of this study was to examine the clinical presentation, management, and outcomes of patients with PPCM using data from a large multicentre heart failure (HF) registry from the Middle East. Methods and results: From February to November 2012, a total of 5005 consecutive patients with HF were enrolled from 47 hospitals in 7 Middle East countries. From this cohort, patients with PPCM were identified and included in this study. Clinical features, in-hospital, and 12 months outcomes were examined. During the study period, 64 patients with PPCM were enrolled with a mean age of 32.5 ± 5.8 years. Family history was identified in 11 patients (17.2%) and hypertension in 7 patients (10.9%). The predominant presenting symptom was dyspnoea New York Heart Association class IV in 51.6%, class III in 31.3%, and class II in 17.2%. Basal lung crepitations and peripheral oedema were the predominant signs on clinical examination (98.2% and 84.4%, respectively). Most patients received evidence-based HF therapies. Inotropic support and mechanical ventilation were required in 16% and 5% of patients, respectively. There was one in-hospital death (1.6%), and after 1 year of follow-up, nine patients were rehospitalized with HF (15%), and one patient died (1.6%). Conclusions: A high index of suspicion of PPCM is required to make the diagnosis especially in the presence of family history of HF or cardiomyopathy. Further studies are warranted on the genetic basis of PPCM.",
keywords = "Cardiomyopathy, Heart failure, Outcomes, Peripartum, Registry, Symptoms",
author = "Salam, {Amar M.} and Ahmed, {Mohamed Badie} and Kadhim Sulaiman and Rajvir Singh and Mohammed Alhashemi and Carr, {Alison S.} and Alsheikh-Ali, {Alawi A.} and AlHabib, {Khalid F.} and Ibrahim Al-Zakwani and Prashanth Panduranga and Nidal Asaad and Abdulla Shehab and Wael AlMahmeed and {Al Suwaidi}, Jassim",
note = "Funding Information: Gulf CARE is an investigator-initiated study conducted under the auspices of the Gulf Heart Association and funded by Servier, Paris, France, and (for centres in Saudi Arabia) by the Saudi Heart Association [The Deanship of Scientific Research at King Saud University, Riyadh, Saudi Arabia (Research Group Number RG-1436-013)]. This does not alter our adherence to policies on sharing data and materials, and the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We would like to thank the Gulf CARE registry investigators,3 data collectors, and staff at all the participating centres for their invaluable efforts and cooperation. Open Access funding was provided by the Qatar National Library. Funding Information: Gulf CARE is an investigator‐initiated study conducted under the auspices of the Gulf Heart Association and funded by Servier, Paris, France, and (for centres in Saudi Arabia) by the Saudi Heart Association [The Deanship of Scientific Research at King Saud University, Riyadh, Saudi Arabia (Research Group Number RG‐1436‐013)]. This does not alter our adherence to policies on sharing data and materials, and the funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Publisher Copyright: {\textcopyright} 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology",
year = "2020",
month = dec,
doi = "10.1002/ehf2.13030",
language = "English",
volume = "7",
pages = "4134--4138",
journal = "ESC heart failure",
issn = "2055-5822",
publisher = "The Heart Failure Association of the European Society of Cardiology",
number = "6",
}