TY - JOUR
T1 - Cardiovascular risk assessment in diabetes mellitus
T2 - Comparison of the general framingham risk profile versus the World Health Organization/ International Society of Hypertension risk prediction charts in Arabs - Clinical implications
AU - Al-Lawati, Jawad A.
AU - Barakat, Mohammed N.
AU - Al-Lawati, Najla A.
AU - Al-Maskari, Masoud Y.
AU - Elsayed, Medhat K.
AU - Mikhailidis, Dimitri P.
AU - Al-Zakwani, Ibrahim S.
PY - 2013/7
Y1 - 2013/7
N2 - We estimated the prevalence of cardiovascular disease (CVD) risk and its clinical implications among 1 110 Omani patients with type 2 diabetes mellitus (DM) using 2 different CVD risk tools: the general Framingham risk profile (GFRP) and the joint World Health Organization/International Society of Hypertension (WHO/ISH) risk prediction charts. The GFRP tool identified higher proportion of patients compared with joint WHO/ISH tool at 10-year CVD risk 10% to <20% and at 20% to <30%. At CVD risk ≥30%, both assessment tools identified similar proportions of patients (22% vs 24%; P=.120). Compared with WHO/ISH charts, the GFRP identified almost double the number of men eligible for aspirin treatment at CVD risk thresholds of ≥10% (86% vs 43%). In women, the proportions were, 66% and 45%, respectively. For statins, the figures were, 60% and 37%, for men and 28% and 36%, for women. In conclusion, the GFRP overestimates the number of patients eligible for primary prevention of CVD compared with the joint WHO/ISH method.
AB - We estimated the prevalence of cardiovascular disease (CVD) risk and its clinical implications among 1 110 Omani patients with type 2 diabetes mellitus (DM) using 2 different CVD risk tools: the general Framingham risk profile (GFRP) and the joint World Health Organization/International Society of Hypertension (WHO/ISH) risk prediction charts. The GFRP tool identified higher proportion of patients compared with joint WHO/ISH tool at 10-year CVD risk 10% to <20% and at 20% to <30%. At CVD risk ≥30%, both assessment tools identified similar proportions of patients (22% vs 24%; P=.120). Compared with WHO/ISH charts, the GFRP identified almost double the number of men eligible for aspirin treatment at CVD risk thresholds of ≥10% (86% vs 43%). In women, the proportions were, 66% and 45%, respectively. For statins, the figures were, 60% and 37%, for men and 28% and 36%, for women. In conclusion, the GFRP overestimates the number of patients eligible for primary prevention of CVD compared with the joint WHO/ISH method.
KW - Oman
KW - World Health Organization/International Society of Hypertension risk prediction chart
KW - cardiovascular disease
KW - diabetes mellitus
KW - general Framingham risk profile
UR - http://www.scopus.com/inward/record.url?scp=84878354683&partnerID=8YFLogxK
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U2 - 10.1177/0003319712458349
DO - 10.1177/0003319712458349
M3 - Review article
C2 - 22942129
AN - SCOPUS:84878354683
SN - 0003-3197
VL - 64
SP - 336
EP - 342
JO - Angiology
JF - Angiology
IS - 5
ER -