Cardiovascular Manifestations and Outcomes in Patients Admitted with Severe COVID-19: Middle Eastern Country Multicenter Data

Fahad Alkindi, Khamis Alhashmi, Sunil Nadar, Salma Alharthi, Khalid Alsaidi, Tasneem Alrashdi, Shabib Alasmi, Feryal Khamis, Adil Algafri, Sultan Allawati, Muzna Alfarsi, Sathiya Murthi, Mujahid Albusaidi, Abdullah Balkhair, Hafidh Alhadi, Khalid Alrasadi, Maather Alabri, Maryam Alissai, Shihab Alkindi, Hilal Alsabti

نتاج البحث: المساهمة في مجلةمراجعة النظراء

ملخص

Objectives: Coronavirus disease-19 (COVID-19) is caused by severe acute respiratory distress syndrome-coronavirus-2 (SARS-CoV-2) -that can affect the cardiovascular system. The aim of our study was to assess the cardiovascular manifestations and its effect on the overall mortality among patients with severe COVID-19 who were admitted in the intensive care units (ICU).

Methods: This is a retrospective, multicenter cohort study that included all adult patients admitted to the ICU with laboratory-confirmed COVID-19 in three major hospitals in Oman between March 1, 2020, and August 10, 2020.

Results: A total of 541 patients (mean age of 50.57 ± 15.57 years; 401 [74.1%] male) were included in the study of which 452 (83.5%) were discharged and 89 (16.5%) died during hospitalization.Evidence of cardiac involvement was found in 185 (34.2%) patients, which included raised troponin (31.6%), arrhythmias (4.3%), myocardial infarctions (2.6%), or drop in ejection fraction (0.9%). High troponin of >100 ng/l was associated with higher mortality (odds ratio [OR] = 7.98; 95% confidence interval [CI]: 4.20-15.15); P < 0.001). Patients with any cardiovascular involvement also had a high risk of dying (OR = 8.8; 95% CI: 4.6-16.5; P < 0.001).

Conclusion: Almost a third of patients in our study had evidence of cardiovascular involvement which was mainly myocardial injury. This was associated with increased mortality.

اللغة الأصليةEnglish
الصفحات (من إلى)20-26
عدد الصفحات7
دوريةHeart views : the official journal of the Gulf Heart Association
مستوى الصوت22
رقم الإصدار1
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يوليو 20 2021

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