Associations between Periodontitis, COVID-19, and Cardiometabolic Complications: Molecular Mechanisms and Clinical Evidence

on behalf of The CArdiometabolic Panel of International Experts on Syndemic COVID-19 (CAPISCO)

نتاج البحث: المساهمة في مجلةReview articleمراجعة النظراء

1 اقتباس (Scopus)


Periodontitis is a microbially driven, host-mediated disease that leads to loss of periodontal attachment and resorption of bone. It is associated with the elevation of systemic inflammatory markers and with the presence of systemic comorbidities. Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the majority of patients have mild symptoms, others experience important complications that can lead to death. After the spread of the COVID-19 pandemic, several investigations demonstrating the possible relationship between periodontitis and COVID-19 have been reported. In addition, both periodontal disease and COVID-19 seem to provoke and/or impair several cardiometabolic complications such as cardiovascular disease, type 2 diabetes, metabolic syndrome, dyslipidemia, insulin resistance, obesity, non-alcoholic fatty liver disease, and neurological and neuropsychiatric complications. Therefore, due to the increasing number of investigations focusing on the periodontitis-COVID-19 relationship and considering the severe complications that such an association might cause, this review aims to summarize all existing emerging evidence regarding the link between the periodontitis-COVID-19 axis and consequent cardiometabolic impairments.

اللغة الأصليةEnglish
رقم المقال40
مستوى الصوت13
رقم الإصدار1
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يناير 2023

ASJC Scopus subject areas

  • ???subjectarea.asjc.2700.2712???
  • ???subjectarea.asjc.1300.1303???
  • ???subjectarea.asjc.1300.1312???

قم بذكر هذا