Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents

Mazaahir Kidwai*, Shilpi Saxena, M. Khalilur Rahman Khan, Sharanjit S. Thukral

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةمراجعة النظراء

418 اقتباسات (Scopus)

ملخص

A simple, clean, environmentally benign route to the synthesis of 2-amino-chromenes is described using K2CO3 as a green catalyst in water under microwave irradiation. This implies a convenient route avoiding the usage of hazardous organic solvents and organic bases. This technique requires only water in both the reaction step and workup, thus rendering the whole procedure into a truly ecofriendly green protocol. All the synthesized compounds were shown to possess antibacterial activity as tested in vitro against standard strains of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.

اللغة الأصليةEnglish
الصفحات (من إلى)4295-4298
عدد الصفحات4
دوريةBioorganic and Medicinal Chemistry Letters
مستوى الصوت15
رقم الإصدار19
المعرِّفات الرقمية للأشياء
حالة النشرPublished - أكتوبر 1 2005
منشور خارجيًانعم

ASJC Scopus subject areas

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بصمة

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