Antibacterial activity of Lawsonia inermis Linn (Henna) against Pseudomonas aeruginosa

O. Habbal, S. S. Hasson*, A. H. El-Hag, Z. Al-Mahrooqi, N. Al-Hashmi, Z. Al-Bimani, M. S. Al-Balushi, A. A. Al-Jabri

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

105 اقتباسات (Scopus)

ملخص

Objective: To investigate the antibacterial activity of henna (Lawsonia inermis Linn) obtained from different regions of Oman against a wide array of micro-organisms. Methods: Fresh henna samples were obtained from different regions of Oman as leaves and seeds. 100 g fresh and dry leaves and 50 g of fresh and dry seeds were separately soaked in 500 mL of ethanol for three days, respectively, with frequent agitation. The mixture was filtered, and the crude extract was collected. The crude extract was then heated, at 48 °C in a water bath to evaporate its liquid content. The dry crude henna extract was then tested for its antibacterial activity using well-diffusion antibiotic susceptibility technique. Henna extracts were investigated for their antibacterial activity at different concentrations against a wide array of different micro-organisms including a laboratory standard bacterial strain of Pseudomonas aeruginosa (NCTC 10662) (P. aeruginosa) and eleven fresh clinical isolates of P. aeruginosa obtained from patients attending the Sultan Qaboos University Hospital (SQUH). 2-Hydroxy-p-Nathoqinone-Tech (2-HPNT, MW=174.16, C10H6O3) was included as control (at 50% concentration) along with the henna samples tested. Results: Henna samples demonstrated antibacterial activity against all isolates but the highest susceptibility was against P. aeruginosa with henna samples obtained from Al-sharqyia region. Conclusions: Omani henna from Al-sharqyia region demonstrates high in vitro anti- P. aeruginosa activity compared with many henna samples from different regions of Oman.

اللغة الأصليةEnglish
الصفحات (من إلى)173-176
عدد الصفحات4
دوريةAsian Pacific Journal of Tropical Biomedicine
مستوى الصوت1
رقم الإصدار3
المعرِّفات الرقمية للأشياء
حالة النشرPublished - يونيو 2011

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