A thirty day course of sodium stibogluconate for treatment of Kala-azar in Nepal

P. Karki*, S. Koirala, S. C. Parija, S. G. Hansdak, M. L. Das

*المؤلف المقابل لهذا العمل

نتاج البحث: المساهمة في مجلةArticleمراجعة النظراء

15 اقتباسات (Scopus)

ملخص

Twenty-seven cases of Kala-azar were treated with sodium stibogluconate at a dose of 20 mg/ kg/day for 20 days (group A) and an equal number of cases were treated with the same dose but for a longer duration of 30 days (group B). Clinical and laboratory evaluation of these cases were carried out before and after therapy, during a follow up of cases every month, upto 6 months. Renal and liver function tests and electrocardiography were carried out of monitor any toxic effect of the drug during therapy. The cure rates of patients were 77.78% and 92.59% in group A and B cases respectively. Six and two patients in group A and B respectively were unresponsive to the treatment and showed relapse. Results of the study show that treatment of cases of Kala-azar with sodium stibogluconate in a dosage of 20 mg/kg/day for a longer period of 30 days is effective with a higher cure rate and minimum side effects, for treatment of cases of Kala-azar in this eastern part of Nepal, endemic for the disease.

اللغة الأصليةEnglish
الصفحات (من إلى)154-158
عدد الصفحات5
دوريةSoutheast Asian Journal of Tropical Medicine and Public Health
مستوى الصوت29
رقم الإصدار1
حالة النشرPublished - مارس 1998
منشور خارجيًانعم

ASJC Scopus subject areas

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